A detailed scene of a patient smiling while doing laughter exercises in a calm clinical environment, demonstrating relief from dry eye symptoms, soft and focused on facial expressions, the patient's eyes are clear and bright, subtle tears forming, with the background showing ophthalmic equipment.
Dry eye disease is a common ailment affecting millions worldwide, and its management often involves artificial tear solutions like sodium hyaluronic acid. However, a new study has brought an alternative treatment into focus: laughter. This randomized controlled trial investigates whether laughter exercises are just as effective in alleviating ocular surface discomfort as conventional treatments.
Understanding the Approach
In this study, participants were divided into two groups. One group received the widely used 0.1% sodium hyaluronic acid eye drops. The other group participated in laughter exercises four times daily for eight weeks. Participants followed an instructional video, vocalizing phrases such as “hee hee hee, hah hah hah” in rhythmic sequences. These laughter exercises were designed to stimulate natural tear production and reduce the symptoms of dry eye.
“After eight weeks, we observed that laughter exercises were non-inferior to sodium hyaluronic acid eye drops in improving ocular surface discomfort,” said Dr. Jing Li, one of the lead researchers. “This suggests that laughter could be a cost-effective, sustainable treatment alternative for patients with dry eye disease.”
Results of the Trial
Out of 299 participants, 283 completed the trial. The study found that laughter exercises decreased the mean ocular surface disease index (OSDI) score by 10.5 points, compared to 8.83 points with sodium hyaluronic acid. The non-inferiority margin of 6 points was met, indicating that laughter exercises were just as effective as the traditional treatment.
Dr. Nathan Congdon, a co-researcher, emphasized, “Laughter not only improved symptoms but also enhanced the non-invasive tear break-up time, a critical measure of tear film stability. These findings are encouraging, particularly for patients seeking more natural or cost-effective alternatives.”
A Safe and Enjoyable Intervention
No adverse events were noted in either group, and participants in the laughter exercise group reported that the treatment was enjoyable. “It’s a novel approach that not only treats dry eye but also adds an element of joy to daily life,” remarked Dr. Lingyi Liang.
The study highlights the potential of laughter as a non-pharmacological, accessible, and affordable method for managing dry eye disease. It offers a sustainable option for patients who may prefer to avoid the long-term use of artificial tears.
Final Thoughts
As more research delves into non-traditional therapies, laughter therapy could pave the way for new, innovative treatments in ocular health. The study’s findings underline the importance of exploring unconventional treatments that enhance both physical and emotional well-being.
Citation: Li J, Liao Y, Zhang SY, et al. Effect of laughter exercise versus 0.1% sodium hyaluronic acid on ocular surface discomfort in dry eye disease: non-inferiority randomised controlled trial. BMJ. 2024;386. doi:10.1136/bmj-2024-080474.
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